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J. Vernon Odom, Ph.D.

Professor

 J. Vernon Odom

304-598-6959

Department

Opthamology, Physiology, and Pharmacology

Graduate Training

University of North Carolina, Greensboro 

Fellowship

Case Western Reserve University School of Optometry, University of California at Berkeley
University of Florida
Netherlands Ophthalmic Research Institute
University of Leuven Institut National de la Sante et Reserche Medicale (INSERM)

Research Interests

My basic research interest is in the assessment of visual function, primarily in humans. I have been particularly interested in higher order visual processes, including binocular vision and optic flow. I use a range of techniques including electrophysiology (electroretinography and visually evoked potientials), psychophysics, and questionnaires. Being in a clinical department, I frequently use my knowledge of visual function either to perform special testing of clinical patients or to evaluate systemic disease effects on the eye. 

Research Topics

Low Vision and Orientation, Mobility, and Action 

One of the major issues in low vision is the ability of patients with low vision to maintain their independence and to avoid accidents. Stated in another way we may ask: how does reducing visual input alter people's ability to navigate and perform visually guided motor tasks, such as pouring a cup of coffee or other activities of daily living? Does the type of impairment, loss of central field, loss of peripheral field, or patchy loss have distinctive effects? What roles do changes in sensitivity to specific visual cues and knowledge (familiarity) with their environment play in people's ability to be mobile and active? Understanding the relationship between low vision, sensitivity to optic flow, and mobility also has important implications for low vision rehabilitation. Are the compensatory strategies that have been developed for rehabilitating low vision patients optimal? Frequently low vision rehabilitation involves prescribing optical devices. Do optical devices compensate for or exacerbate a way of overcoming difficulties?

Optic Flow and Mobility

One of the major clues for determining one's visual direction or heading is optic flow, i.e., the relativechange in positions of objects at different places in the visual field as one moves. In an optic flow field there is a point from which all of the changes flow. As one moves forward, this point does not change. This stationary point of expansion (POE) is the point toward which the person is heading. To the best of our knowledge there are no studies that determine the sensitivity of low vision patients to optic flow information or compare their sensitivity to that of age-matched controls. These simple demonstrations will be the initial step in our research program. They will be followed by studies, which determine the relationship between an individual patient's ability to detect optic flow information and their ability to perform simple mobility tasks. 

Understanding Binocular Vision 

Understanding binocular vision and the influence of parallel visual processing is a continuing research interest. We have developed a model of binocular luminance interaction based on evoked potential and psychophysical studies in humans and nonhuman primates (see figure). This continuing interest in binocular vision forms the basis of collaboration with Dr. Janine Mendola’s projects on fMRI imaging of amblyopia.


Lab Personnel and Collaborators

Collaborators 

Janine Mendola, PhD
Assistant Professor
McGill Vision Research Department of Ophthalmmology 
McGill University

Lab Personnel

Homer Humble
Research Assistant
304-598-4934  
humbleh@rcbhsc.wvu.edu

Publications

Publications in Peer Reviewed Journals (selected from 82)

 Halfeld Furtado de Mendonça, R, Abbruzzese S,  Bagolini B,  Italo Nofroni I,  Ferreira EL, Odom JV. Visual evoked potential importance in the complex mechanism of amblyopia.
International Ophthalmology (The International Journal of Clinical Ophthalmology and Visual Sciences), in press.

Takaaki, K.,   Tillman, W.T., Schwartz, T.L., Linberg, J.V., Odom, J.V.  Health Related Quality of Life after Surgical Removal of An Eye. Ophthalmic Plastic and Reconstructive Surgery, 2013, 29(1), 51-6

Wiley, L., McAllister, M., Wiley, L.A., Elliott, T., Bridge, D., Odom, J.V., Olson, J. Bacterial Biofilm Diversity in Contact Lens-Related Disease: Emerging Role of Achromobacter, Stenotrophomonas, and Delftia Investigative Ophthalmology and Visual Science, 2012, 53, 3896-3905; doi:10.1167/iovs.11-8762

Wu, F., Yang, Yb. Li, Hj. Odom, J.V. Chromatic visual-evoked potentials in central serous chorioretinopathy patients: Relationship to the changes of foveal photoreceptor layer. Ophthalmic and Physiological Optics, 2011, 31(4), 381-388.

Odom JV, Bach M, Brigell M, Holder GE, McCulloch DL, Tormene AP, Vaegan. ISCEV standard for clinical visual evoked potentials (2009 update). Doc Ophthalmol. 2010 Feb;120(1):111-9. Epub 2009 Oct 14.

Connor IP, Odom JV, Schwartz TL, Mendola JD. Retinotopic maps and foveal suppression in the visual cortex of amblyopic adults. J Physiol. 2007 Aug 15;583(Pt 1):159-73. Epub 2007 Jul 12.

Connor IP, Odom JV, Schwartz TL, Mendola JD. Monocular activation of V1 and V2 in amblyopic adults measured with f unctional magnetic resonance imaging. J AAPOS. 2007 Aug;11(4):341-50. Epub 2007 Apr 16.

Odom, J.V., Odom, C.V., and Leys, M.J. Does improving vision reduce the risk of falls? A review.  Insight: Research & Practice in Visual Impairment & Blindness. 2011, 4(2), 92-99.

Odom, J.V., Bach, M., Brigell. M., Holder, G.E., McCulloch, D. L., Tormene, A.P., and Vaegan (for the International Society for Clinical Electrophysiology of Vision). ISCEV standard for clinical visual evoked potentials - (2009 update). Documenta Ophthalmologica, 2010, 120, 111–119.

Connor, I.P, Odom J.V., Schwartz T., and Mendola, J.D.  Monocular activation of V1 and V2 in amblyopic adults measured with functional magnetic resonance imaging. Journal of the American Association for Pediatric Ophthalmology and Strabismus,   2007, 11, 341-350. (Available online 16 April 2007).

Conner, I.P.,  Odom, J.V., Schwartz, T.L., and Mendola, J.D. Retinotopic maps and foveal suppression in the visual cortex of amblyopic adults. Journal of  Physiology (London). 2007, 583, 159-173. (First published online 21 June 2007)

Walter, C., Althouse, R., Humble H., Smith, W., and Odom, J.V. Vision rehabilitation: Recipients’ perceived efficacy of rehabilitation. Ophthalmic Epidemiology, 2007, 14, 103–111.

Adjeroh, D., Kandaswamy, U., and Odom, J.V. Texton-based segmentation of retinal vessels. Journal of the Optical Society of America – A, 2007, 24, 384-1393.  posted 11/14/2006; Doc. ID 73906.

Jabbour, J., Jabbour, N.M., Villers, A., and Odom, V. 25-Gauge Vitrectomy.  Ophthalmology, 2007, 114, 827.e1-827.e2

Agrawal R, Conner IP, Odom JV, Schwartz TL, Mendola JD. Relating binocular and monocular vision in strabismic and anisometropic amblyopia. Archives of Ophthalmology (2006), 124:844-850.

El-Sherbeeny AM, Odom JV, Della-Giustina D, Smith JE. Eye biomarkers as early indicators of occupational toxicity: blood toxins, heavy metals, and neurotoxins. Professional Safety: Journal of the American Society of Safety Engineers (2006), 41:26-32.

El-Sherbeeny AM, Odom JV, Smith JE. Ocular manifestations due to systemic exposure to mercury. Journal of Toxicology: Cutaneous and Ocular Toxicology (2006), 25:173-183.

El-Sherbeeny AM, Odom JV, Smith JE. Spatial density distribution as a basis for image compensation. Journal of Modern Optics (2006), 53:1241-1244.

Odom JV, Ghude P, Humble H. Effect of prism orientation on heading detection in optic flow. Journal of Modern Optics (2006), 53:1365-1371.

Odom JV, Leys MJ, Charlton J, Manahilov V, Green M. Detecting glaucomatous damage: evaluation with contrast independent tasks. Journal of Modern Optics (2006), 53:1373-1385.

Van Scoy FA, McLaughlin D, Odom JV, Walls RT, Zeppuhar ME. Touching mathematics: a prototype tool for teaching pre-calculus to visually impaired students. Journal of Modern Optics (2006), 53:1287-1294.

Mendola JD, Conner IP, Roy A, Chan ST, Schwartz TL, Odom JV, Kwong KK. Voxel-based analysis of MRI detects abnormal visual cortex in children and adults with amblyopia. Human Brain Mapping (2005), 25(2):222-236.

Molnar LR, Odom JV, DeRoos BG, Kolanko CJ. Ocular scanning instrumentation: rapid diagnosis of chemical threat agent exposure. Proceedings of the SPIE (2004), 5403:60-67.

Odom JV, Bach M, Barber C, Brigell M, Marmor MF, Tormene AP, Holder GE, Vaegan. Visual evoked potentials standard (2004). Documenta Ophthalmologica (2004), 108(2):115-123.

Walter C, Althouse R, Humble H, Leys MJ, Odom JV. West Virginia survey of visual health: low vision and barriers to access. Visual Impairment Research (2004), 6:53-71.

Molnar LR, Henry KA, Odom JV, Kolanko CJ. Ocular scanning instrumentation: confirmation of biomarkers for anticholinesterase and cyanide exposure. Proceeding of SPIE: Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Defense and Law Enforcement II (2003), 5071:33-40.

Odom JV. Functional vision: assessment and outcome. Visual Impairment Research (2003), 5:113-114.

Springs CL, Joseph MA, Odom JV, Wiley LA. Predictability of donor lamellar graft diameter and thickness in an artificial anterior chamber system. Cornea (2002), 21(7):696-699.

Odom JV. Vision, visual needs, and quality of life in older persons in rural environments: a report and synthesis of a meeting. Journal of Rural Aging (2001), 17(4):360-363.

 

 

 

Recent: Book Chapters, Proceedings and Editorials (selected from 47)

Brodie, S., Odom, J.V., and Leys, M.J.J.  Clinical Visual Electrophysiology.  In W. Tasman and E.A. Jaeger (eds.).  Duane's Clinical Ophthalmology. Vol. 3. Chapter 5, Philadelphia, PA:  J.B. Lippincott Co., 2011.

Odom, J. V. and Green M.  Visual Aging and Driving. Marc Green, Merrill J. Allen, Bernard S. Abrams, Leslie Weintraub and J. Vernon Odom. Forensic Vision: With Application to Highway Safety.  3rd ed.  Tucson, Az: Lawyers & Judges Publishing, 2008.

Odom, J.V. Amplifiers and special purpose data acquisition systems. In Heckenlively J, Arden G, eds. Handbook of Clinical Electrophysiology of Vision Testing, 2nd Ed. The MIT Press: Cambridge, MA (2006).

Odom, J.V. Kernel analysis.In Heckenlively J, Arden G, eds. Handbook of Clinical Electrophysiology of Vision Testing, 2nd Ed. The MIT Press: Cambridge, MA (2006).

Walter, C., Humble, H, Althouse ,R, Odom, J.V. A comparison of low-vision patients from a clinic and a random sample of West Virginians: demographics, treatment patterns, vision problems, and activities of daily living. In Jones S, Rubin G, Hamlin D, eds. Vision 2005— Proceedings of the International Congress held between 4–7 April 2005 in London, UK, International Congress Series (2006), 1282:462-465.

Adjeroh, D., Kandaswamy, U., and Odom, J.V. Texton-based segmentation of retinal vessels. Journal of the Optical Society of America – A, 2007, 24, 384-1393.  posted 11/14/2006; Doc. ID 73906.

Jabbour, J., Jabbour, N.M., Villers, A., and Odom, V. 25-Gauge Vitrectomy.  Ophthalmology, 2007, 114, 827.e1-827.e2

Agrawal R, Conner IP, Odom JV, Schwartz TL, Mendola JD. Relating binocular and monocular vision in strabismic and anisometropic amblyopia. Archives of Ophthalmology (2006), 124:844-850.

El-Sherbeeny AM, Odom JV, Della-Giustina D, Smith JE. Eye biomarkers as early indicators of occupational toxicity: blood toxins, heavy metals, and neurotoxins. Professional Safety: Journal of the American Society of Safety Engineers (2006), 41:26-32.

El-Sherbeeny AM, Odom JV, Smith JE. Ocular manifestations due to systemic exposure to mercury. Journal of Toxicology: Cutaneous and Ocular Toxicology (2006), 25:173-183.

El-Sherbeeny AM, Odom JV, Smith JE. Spatial density distribution as a basis for image compensation. Journal of Modern Optics (2006), 53:1241-1244.

Odom JV, Ghude P, Humble H. Effect of prism orientation on heading detection in optic flow. Journal of Modern Optics (2006), 53:1365-1371.

Odom JV, Leys MJ, Charlton J, Manahilov V, Green M. Detecting glaucomatous damage: evaluation with contrast independent tasks. Journal of Modern Optics (2006), 53:1373-1385.

Van Scoy FA, McLaughlin D, Odom JV, Walls RT, Zeppuhar ME. Touching mathematics: a prototype tool for teaching pre-calculus to visually impaired students. Journal of Modern Optics (2006), 53:1287-1294.

Mendola JD, Conner IP, Roy A, Chan ST, Schwartz TL, Odom JV, Kwong KK. Voxel-based analysis of MRI detects abnormal visual cortex in children and adults with amblyopia. Human Brain Mapping (2005), 25(2):222-236.

Molnar LR, Odom JV, DeRoos BG, Kolanko CJ. Ocular scanning instrumentation: rapid diagnosis of chemical threat agent exposure. Proceedings of the SPIE (2004), 5403:60-67.

Odom JV, Bach M, Barber C, Brigell M, Marmor MF, Tormene AP, Holder GE, Vaegan. Visual evoked potentials standard (2004). Documenta Ophthalmologica (2004), 108(2):115-123.

Walter C, Althouse R, Humble H, Leys MJ, Odom JV. West Virginia survey of visual health: low vision and barriers to access. Visual Impairment Research (2004), 6:53-71.

Molnar LR, Henry KA, Odom JV, Kolanko CJ. Ocular scanning instrumentation: confirmation of biomarkers for anticholinesterase and cyanide exposure. Proceeding of SPIE: Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Defense and Law Enforcement II (2003), 5071:33-40.

Odom JV. Functional vision: assessment and outcome. Visual Impairment Research (2003), 5:113-114.

Springs CL, Joseph MA, Odom JV, Wiley LA. Predictability of donor lamellar graft diameter and thickness in an artificial anterior chamber system. Cornea (2002), 21(7):696-699.

Odom JV. Vision, visual needs, and quality of life in older persons in rural environments: a report and synthesis of a meeting. Journal of Rural Aging (2001), 17(4):360-363.

Recent: Book Chapters, Proceedings and Editorials (selected from 47)

Brodie, S., Odom, J.V., and Leys, M.J.J.  Clinical Visual Electrophysiology.  In W. Tasman and E.A. Jaeger (eds.).  Duane's Clinical Ophthalmology. Vol. 3. Chapter 5, Philadelphia, PA:  J.B. Lippincott Co., 2011.

Odom, J. V. and Green M.  Visual Aging and Driving. Marc Green, Merrill J. Allen, Bernard S. Abrams, Leslie Weintraub and J. Vernon Odom. Forensic Vision: With Application to Highway Safety.  3rd ed.  Tucson, Az: Lawyers & Judges Publishing, 2008.

Odom, J.V. Amplifiers and special purpose data acquisition systems. In Heckenlively J, Arden G, eds. Handbook of Clinical Electrophysiology of Vision Testing, 2nd Ed. The MIT Press: Cambridge, MA (2006).

Odom, J.V. Kernel analysis.In Heckenlively J, Arden G, eds. Handbook of Clinical Electrophysiology of Vision Testing, 2nd Ed. The MIT Press: Cambridge, MA (2006).

Walter, C., Humble, H, Althouse ,R, Odom, J.V. A comparison of low-vision patients from a clinic and a random sample of West Virginians: demographics, treatment patterns, vision problems, and activities of daily living. In Jones S, Rubin G, Hamlin D, eds. Vision 2005— Proceedings of the International Congress held between 4–7 April 2005 in London, UK, International Congress Series (2006), 1282:462-465.